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Eosinophilic fasciitis: A case report

机译:嗜酸性粒细胞性筋膜炎的病例报告

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摘要

Eosinophilic fasciitis is a rare connective tissue disease. It is characterized by a progressive and symmetrical induration and thickening of the skin and soft tissues of the limbs. In addition to the skin manifestations, the joints and muscles are also involved, and in rare cases there can be systemic involvement. The diagnosis of EF is based on clinical findings, the presence of peripheral blood eosinophilia, and a full-thickness biopsy that should include the deep fascia in order to show the inflammatory infiltration that is mostly composed of lymphocytes and eosinophils.Systemic corticosteroids remain the treatment of choice and may be combined with an immunosuppressive drug.
机译:嗜酸性粒细胞性筋膜炎是一种罕见的结缔组织病。它的特征是四肢皮肤和软组织的进行性和对称性硬结和增厚。除了皮肤表现外,关节和肌肉也受累,在极少数情况下可能会全身受累。EF 的诊断基于临床表现、外周血嗜酸性粒细胞增多的存在以及应包括深筋膜的全层活检,以显示主要由淋巴细胞和嗜酸性粒细胞组成的炎症浸润。全身性皮质类固醇仍然是首选治疗药物,可与免疫抑制药物联合使用。

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