A new metabolite from the endophytic fungus Penicillium citrinum

摘要

A new polyketide, penicillocitrin A (1), together with four known compounds, was isolated from the endophytic fungus Penicillium citrinum (CTGU-TS-24) of Tapiscia sinensis Oliv., and their structures were elucidated by NMR spectroscopic and MS spectrums. The five compounds were evaluated cytotoxic activity to four cancer cell lines A549, Hep G2, Hela and Caski at different levels.