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Anticoagulation in Mechanical Circulatory Support

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Purpose of Review The field of mechanical circulatory support is rapidly evolving, and along with it, the management of anticoagulation and hemocompatibility also changes. The purpose of this review is to provide a contemporary approach to the evaluation and management of anticoagulation in mechanical circulatory support device therapies. Recent Findings Important recent studies and guidelines have solidified a more uniform approach to anticoagulation in both temporary and durable devices. With advances in technology, it may be possible to reduce the requirements for anticoagulant and antiplatelet therapies. Though there are new technologies and management strategies being utilized, hemocompatibility between a patient and their mechanical circulatory support device remains of paramount importance for acceptable outcomes after device implantation. This must be individualized to each patient and performed within the context of a dedicated multidisciplinary team.

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