Immunohistochemistry study on citoarchitectural modifications at placental level in case of developmental disorders and prematurity

摘要

The hereby study aims to be a retrospective, a summary of a study on placental structural changes outlined by new researches from more than ten years. The studied lot has a statistical value being balanced, with the clinical laboratory and evolutionary arguments sufficient to allow an accurate analysis, and is representative of the studied problems, represented by morphological changes that correlate with different physiological placental variety of impaired intrauterine growth and development and perinatal consequences. Also the lot allowed through the included categories to make an analysis of placental citoarchitecture and of the fetoplacentar unit in order validate the study findings. I made these remarks because in multiple situations the analysis of morphological placenta was insufficient or superficial, losing the valuable information on product evolution and prognosis from a conceptual task with increased risk or no risk. Immunohistochemical study shows superiority in identifying structural changes of cellular and tissue intimacy at the placental level compared with morphological and histochemical methods.