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Notes On Compound Biology Meets Biological Chemistry

机译:关于化合物生物学与生物化学的结合笔记

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摘要

It is the study of chemical processes inside and about living organisms. A sub-discipline of each chemistry and biology, organic chemistry could also be divided into 3 fields: structural biology, biochemistry, and metabolism. Over the last decades of the twentieth century, organic chemistry has become eminent at explaining living processes through these 3 disciplines. most areas of the life sciences are being uncovered and developed through organic chemistry methodology and analysis 1. Biochemistry focuses on understanding the chemical basis that permits biological molecules to present rise to the processes that occur inside living cells and between cells, successively relating greatly to the understanding of tissues and organs, further as organism structure and performance. Biochemistry is closely associated with biological science, that is that the study of the molecular mechanisms of biological phenomena. organic chemistry is each bioscience and a natural science - it explores the chemistry of living organisms and therefore the molecular basis for the changes occurring in living cells. Much of organic chemistry deals with the structures, bonding, functions, and interactions of biological macromolecules, like proteins, nucleic acids, carbohydrates, and lipids 2. they supply the structure of cells and perform several of the functions related to life. The chemistry of the cell conjointly depends upon the reactions of tiny molecules and ions. These may be inorganic (for example, water and metal ions) or organic (for example, the amino acids, that are to synthesize proteins). The mechanisms employed by cells to harness energy from their atmosphere via chemical reactions are called metabolism. The findings of organic chemistry are applied primarily in drugs, nutrition, and agriculture. In drugs, biochemists investigate the causes and cures of diseases. Nutrition studies the way to maintain health and upbeat and conjointly the results of nutritionary deficiencies. In agriculture, biochemists investigate soil and fertilizers. up crop cultivation, crop storage, and pesterer management also are goals 3. it had been once usually believed that life and its materials had some essential property or substance (often cited because the "vital principle") distinct from any found in non-living matter, and it had been thought that solely living beings might turn out the molecules of life. In 1828, Friedrich Wohler revealed a paper on his lucky organic compound synthesis from K cyanate and ammonium ion sulfate; some regarded that as an on-the-spot overthrow of philosophical doctrine and therefore the institution of chemical science. However, the W枚hler synthesis has sparked difference as some reject the death of philosophical doctrine at his hands. Since then, organic chemistry has advanced, particularly since the mid-20th century, with the event of latest techniques like action, diffraction, twin polarization interferometry, proton magnetic resonance spectrum analysis, radio isotopic labeling, microscopy, and molecular dynamics simulations. These techniques allowed for the invention and elaborated analysis of the many molecules and metabolic pathways of the cell, like metabolic process and therefore the citric acid cycle (citric acid cycle), Associate in Nursing LED to an understanding of organic chemistry on a molecular level.
机译:它是对生物体内和生物体内部的化学过程的研究。有机化学是化学和生物学的分支学科,也可以分为结构生物学、生物化学和新陈代谢3个领域。在二十世纪的最后几十年里,有机化学在通过这 3 个学科解释生命过程方面变得非常出色。生命科学的大多数领域都是通过有机化学方法和分析来发现和发展的[1]。生物化学侧重于理解允许生物分子呈现在活细胞内部和细胞之间发生的过程的化学基础,依次与对组织和器官的理解密切相关,进一步作为生物体的结构和性能。生物化学与生物科学密切相关,即研究生物现象的分子机制。有机化学既是生物科学,又是一门自然科学——它探索生物体的化学性质,从而探索活细胞中发生的变化的分子基础。许多有机化学涉及生物大分子(如蛋白质、核酸、碳水化合物和脂质)的结构、键合、功能和相互作用[2]。它们提供细胞的结构并执行与生命相关的多种功能。细胞的化学性质共同取决于微小分子和离子的反应。这些可以是无机的(例如,水和金属离子)或有机的(例如,用于合成蛋白质的氨基酸)。细胞通过化学反应从大气中获取能量的机制称为新陈代谢。有机化学的研究结果主要应用于药物、营养和农业。在药物中,生物化学家研究疾病的原因和治疗方法。营养学研究保持健康和乐观的方法,并结合营养缺乏的结果。在农业中,生物化学家研究土壤和肥料。提高作物种植、作物储存和缠绕者管理也是目标[3]。人们曾经通常认为,生命及其材料具有一些与非生命物质不同的基本属性或物质(经常被引用,因为“生命原理”),并且人们认为只有生物才能产生生命的分子。1828年,弗里德里希·沃勒(Friedrich Wohler)发表了一篇关于他从氰酸钾和硫酸铵离子合成有机化合物的论文;一些人认为这是对哲学学说的当场推翻,因此也是对化学科学制度的推翻。然而,W枚赫勒的综合引发了分歧,因为一些人拒绝哲学学说在他手中的死亡。从那时起,有机化学取得了进步,特别是自 20 世纪中叶以来,随着动作、衍射、双偏振干涉测量、质子磁共振频谱分析、放射性同位素标记、显微镜和分子动力学模拟等最新技术的出现。这些技术允许对细胞的许多分子和代谢途径进行发明和详细分析,如代谢过程,因此柠檬酸循环(柠檬酸循环),护理 LED 在分子水平上理解有机化学。

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  • 来源
    《Industrial Chemistry》 |2022年第3期|1-2|共2页
  • 作者

    Tom Brown;

  • 作者单位

    Department of Nucleic Acid Chemistry, University of Oxford;

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  • 原文格式 PDF
  • 正文语种 英语
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