Can we correlate pelvic floor dysfunction severity on MR defecography with patient-reported symptom severity?

摘要

abstract_textpMR defecography (MRD) is an alternative to conventional defecography (CD) which allows for dynamic visualisation of the pelvic floor. The aim of this study was to assess whether MRI features indicative of pelvic floor dysfunction correlated with patient-reported symptom severity. MR proctograms were matched to a prospectively-maintained functional database. Univariate and multivariate analyses were performed using pre-treatment questionnaire responses to the Birmingham Bowel, Bladder and Urinary Symptom Questionnaire (BBUSQ), Wexner Incontinence Score (WIS), and modified Obstructed Defecation Symptom (ODS) Score. 302 MRI proctograms were performed between January 2012 and April 2015. 170 patients were included. Patients with a rectocele2cm (p=0.003; OR 5.756) or MRD features suggestive of puborectalis syndrome (p=0.025; OR 8.602) were more likely to report a higher ODS score on multivariate analysis. Lack of rectal evacuation was negatively associated with an abnormal WIS (p=0.007; OR 0.228). Age50 (p=0.027, OR 2.204) and a history of pelvic floor surgery (p=0.042, OR 0.359) were correlated with an abnormal BBUSQ incontinence score. Lack of rectal evacuation (p=0.027, OR 3.602) was associated with an abnormal BBUSQ constipation score. Age50 (p=0.07, OR 0.156) and the presence of rectoanal intussusception (p=0.010, OR 0.138) were associated with an abnormal BBUSQ evacuation score. Whilst MRD is a useful tool in aiding multidisciplinary decision making, overall, it is poorly correlated with patient-reported symptom severity, and treatment decisions should not rest solely on results./p/abstract_text