Polymorphic variations in theorisequences from the mitochondrial genomes of different wild-type yeast strains

摘要

We determined the restriction maps and primary structures of two as yet poorly characterized regions of the mitochondrial genomes of different wildtype strains ofSaccharomyces cerevisiae. These regions respectively comprised theori1 sequence and the newly identifiedori8 sequence.Ori1 andori8, together with their flanking sequences, exhibit a large polymorphism, resulting from specific variations due to insertions or deletions of optional GC clusters at different locations. The mechanisms underlying such sequence rearrangements are discussed.