The prenatal development of the pulvinar in the monkey:3H-thymidine autoradiographic and morphometric analyses

摘要

The genesis and development of the pulvinar in monkey (Macaca mulatta) was studied by means of tritiated thymidine (3H-TdR) autoradiography and by examination and morphometric analysis of Nissl stained histological sections. The time of origin was determined by analysis of labeled cells in the pulvinar of monkeys that had been exposed to3H-TdR at various embryonic (E) days and sacrificed 2–3 months after birth, which in this species occurs around E165. Heavily labeled pulvinar neurons were observed only in animals that had been exposed to3H-TdR between E36 and E45. Onset of genesis for neurons that comprise the inferior and adjacent areas of lateral pulvinar precedes the onset in the remainder of lateral and medial pulvinar by two day