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The Evaluation of Psychopharmacological Enhancers Beyond a Normative 'Natural'-'Artificial' Dichotomy

机译:超越标准“自然”-“人工”二分法的心理药物增强剂的评估

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The extra-therapeutic use of psychotropic drugs to improve cognition and to enhance mood has been the subject of controversial discussion in bioethics, in medicine but also in public for many years. Concerns over a liberal dealing with pharmacological enhancers are raised not only from a biomedical-pharmacological perspective, but particularly from an ethical one. Within these ethical concerns, there is one objection about the normative differentiation between "natural" and "artificial" enhancers, which is theoretically indeed widely discredited in bioethics, which has, however, entrenched itself in such a persistent way in everyday moral consciousness that it keeps a crucial influence on the assessment of pharmacological enhancers made by the public and medical professionals. This paper tries to first show why a normative differentiation between "natural" and "artificial" enhancers is highly problematic. In a second step, the resulting implications for our current dealing with pharmacological enhancers shall be examined. In a specific comparison of synthetic pharmaceuticals (modafinil, SSRIs) with phytopharmaceuticals (ginkgo biloba, St. John's wort) and other already established enhancers (alcohol, caffeine), argumentative inconsistencies are pointed out which, at least partly, result from a rationally untenable preference for the "natural" over the "artificial". Therefore, it is conclusively argued the case for an unprejudiced assessment of pharmacological enhancers beyond a "natural"-"artificial" dichotomy, which equally takes into account biomedical and ethical aspects. The goal is to reach a coherent dealing with pharmacological enhancement in the long run.
机译:精神药物在治疗外的使用以改善认知和改善情绪一直是生物伦理学,医学界乃至公众的有争议的话题。不仅从生物医学-药理学的角度,而且特别是从伦理学的角度,提出了对药理增强剂的自由化处理的担忧。在这些伦理问题中,有人对“自然”和“人工”促进剂之间的规范区别提出异议,这在理论上确实在生物伦理学中被广泛抹黑,然而,它在日常道德意识中以一种持久的方式根深蒂固,对公众和医学专业人员进行的药理增强剂评估具有至关重要的影响。本文试图首先说明为什么“天然”和“人工”增强剂之间的规范区分存在很大问题。在第二步中,应检查对我们当前与药理增强剂的关系所产生的影响。在合成药物(莫达非尼,SSRIs)与植物性药物(银杏叶,圣约翰草)和其他已经建立的增强剂(酒精,咖啡因)的特定比较中,指出了争论的不一致,至少部分是由于理性上的不合理造成的相对于“人工”,偏爱“自然”。因此,有争议的是,除了“自然”-“人工”二分法外,对药理增强剂进行无偏见的评估是必要的,后者同样考虑了生物医学和伦理学方面。从长远来看,目标是达成一致的药理增强处理。

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