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A practical method for real-time detection of pedicle wall breaching during funneling

机译:一种实时检测漏斗过程中椎弓根壁破裂的实用方法

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Abstract Background A reliable, real-time method for the detection of pedicle wall breaching during funnelling in spine deformity surgery could be accessible to any surgeon assisted with neuromonitoring.Methods Fifty-six consecutive patients (1066 pedicles), who were submitted to spinal deformity surgery from December 2013 to July 2015 were included in the study group. A control group of 13 consecutive patients (226 pedicles) with spinal deformity surgery were operated on from January to December 2013 and were excluded from finder stimulation. In the study cohort, continuous stimulation during funnelling was delivered via a finder and subsequently a compound muscle action potential (CMAP) threshold was determined. Following funnelling, manual inspection of the pedicular internal walls was performed. The CMAP thresholds were compared with the results of palpation to determine the sensitivity and specificity of the technique for detecting pedicular breaching. To cover common ranges of damage, the medial and lateral breaches were compared and the concave-apical breaches compared to the non-apical or convex-apical breaches. In addition, a pedicle screw test was estimated for all patients.Results ROC analysis showed 9?mA cut-off to have a sensitivity of 88.0 and a specificity of 89.5 for predicting pedicular breaching, with an area under the curve of 0.92 (95 confidence interval 0.90–0.94; P?
机译:摘要 背景 任何在神经监测辅助下的外科医生都可以使用一种可靠的实时方法来检测脊柱畸形手术漏斗期间椎弓根壁破裂。方法 选取2013年12月至2015年7月连续接受脊柱畸形手术的56例患者(1066个椎弓根)。2013 年 1 月至 12 月对 13 例连续 13 例脊柱畸形手术患者(226 个椎弓根)进行手术的对照组,被排除在发现器刺激之外。在研究队列中,通过发现器在漏斗期间提供连续刺激,随后确定复合肌肉动作电位 (CMAP) 阈值。漏斗后,对椎弓根内壁进行手动检查。将CMAP阈值与触诊结果进行比较,以确定检测椎弓根破坏的技术的敏感性和特异性。为了涵盖常见的损伤范围,比较了内侧和外侧的突破,并将凹顶突破与非顶端或凸顶端的突破进行了比较。此外,估计对所有患者进行椎弓根螺钉试验。结果 ROC分析显示,9?mA临界值对预测椎弓根破坏的敏感性为88.0%,特异性为89.5%,曲线下面积为0.92(95%置信区间0.90–0.94;P?0.001)。以9?mA阈值为警戒标准,与非顶端和凸顶端蒂相比,凹顶椎弓根处漏斗的真假警示显著增加,真阴性警示少(P?0.001)。内侧突破的刺激阈值显著低于外侧突破(P?0.001)。研究的螺钉试验阈值显著高于对照组患者(P?=?0.002)。结论 Finder刺激对预测椎弓根破裂具有更高的敏感性和特异性,在内侧破坏中最为突出。与对照组相比,螺钉试验显示,在接受发现器刺激技术的患者中,结果明显更好。我们方法的主要优点是安全性高、成本低,这在不太富裕的国家可能至关重要。证据水平 III.

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