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Prospective survey of secondary bleeding following anorectal surgery in a consecutive series of 1,269 patients

机译:连续1269例肛门直肠手术后继发性出血的前瞻性调查

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Introduction: As little data is available about secondary bleeding after proctological surgery, we conducted a specific survey.Patients and methods: Patients operated between November 2008 and April 2009 were prospec-tively included. Patients were followed until last visit (day 21-28). Severity of bleeding was low (at home stay), moderate (hospitalisation for observation), or severe (transfusion, and/or homeostasis in operating room).Results: Included were 1269 patients: haemorrhoidectomy/pexy 527 (41%), fistula treatment 273 (21%), fissurectomy 197 (15%), perianal and pilonidal abscesses 124 (10%), others 148 (12%). Before surgery 78 patients were under long-term treatment with antiplatelet or anticoagulant therapy. Seventy-eight patients (6%) demonstrated 85 bleeding events. Severity rate was: low 22%, moderate 51%, and severe 27%. Ninety-five percent of events occurred before day 15. Univariate study showed increased risk after haemorrhoidopexy (P<10~(-3)) and anticoagulant treatment (P = 0.002), decreased risk after fissurectomy and fistulotomy (P< 10~(-3)), and no relation with age, sex or operator. After multivariate study only relationship with anticoagulant treatment remained significant.Conclusion: Secondary bleeding occurred in 6% of patients after proctological surgery, requiring a readmission and /or an active treatment in about 75%. Treatment with anticoagulant exposed to increased bleeding frequency.
机译:简介:由于关于直肠外科手术后继发性出血的数据很少,我们进行了一项具体调查。患者和方法:预期包括2008年11月至2009年4月之间手术的患者。随访患者直到最后一次就诊(第21-28天)。出血严重程度低(在家中),中度(住院以观察)或严重(输血和/或在手术室中达到稳态)结果:包括1269例患者:痔切除术/ pexy 527(41%),瘘管治疗273(21%),fissurectomy 197(15%),肛周和毛发脓肿124(10%),其他148(12%)。手术前有78例患者长期接受抗血小板或抗凝治疗。 78名患者(6%)表现出85次出血事件。严重程度为:低22%,中度51%和严重27%。 95%的事件发生在第15天之前。单因素研究显示,痔疮术后(P <10〜(-3))和抗凝治疗(P = 0.002)的风险增加,裂隙切除术和阴囊切开术后的风险降低(P <10〜(- 3)),并且与年龄,性别或操作员无关。经过多变量研究后,与抗凝治疗的关系仍然很显着。结论:直肠手术后6%的患者发生继发性出血,需要再次入院和/或积极治疗的患者约占75%。用抗凝剂治疗会增加出血频率。

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