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The metabolic syndrome and its components in postmenopausal women

机译:绝经后妇女的代谢综合征及其组成

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Background: Prevalence of the metabolic syndrome (METS) increases significantly after the menopause. Objective: To assess the prevalence of the METS and its components in postmenopausal women. Factors relating to each of the composing items of the METS were also analyzed. Methods: Natural postmenopausal women (40-65 years) were invited to participate in this cross-sectional study in order to assess the presence of the METS using modified Adult Treatment Panel III (ATP-III) criteria. Participants were also requested to fill out a general socio-demographic questionnaire. Results: A total of 204 women were surveyed with a median age of 56 years. A 52.9% presented the METS according to modified ATP-III criteria, with 37.3% presenting hyperglycemia, 51.5% hypertension, 58.3% abdominal obesity, 45.6% high triglyceride levels and 56.4% low HDL-C levels. Women with the METS presented a higher rate of dyslipidemia (high triglyceride and low HDL-C levels), hyperglycemia, hypertension and abdominal obesity than those without the syndrome. Those with abdominal obesity and hyperglycemia significantly displayed higher rates of low HDL-C levels (bivariate analysis). Multiple linear regression analysis found a positive correlation between glucose and triglyceride levels. Systolic blood pressure significantly and positively correlated to age and abdominal circumference. Abdominal circumference displayed an inverse correlation with educational level. Conclusion: Prevalence of the METS in this postmenopausal female sample was high and associated to metabolic and lipid derangements. As abdominal obesity was significantly associated to lower education, there is an urgent need of implementing educational programs directed to high-risk populations in order to increase awareness of the problem.
机译:背景:绝经后代谢综合征(METS)的患病率显着增加。目的:评估绝经后妇女中METS及其成分的患病率。还分析了与METS的每个组成项目有关的因素。方法:邀请绝经后的自然妇女(40-65岁)参加这项横断面研究,以使用改良的成人治疗小组III(ATP-III)标准评估METS的存在。还要求参与者填写一份一般的社会人口统计调查表。结果:总共调查了204位女性,中位年龄为56岁。 52.9%的人根据改良的ATP-III标准提供了METS,其中37.3%的人具有高血糖,51.5%的高血压,58.3%的腹部肥胖,45.6%的甘油三酸酯高和56.4%的HDL-C低。与没有该综合征的女性相比,患有METS的女性具有更高的血脂异常(高甘油三酯和低HDL-C水平),高血糖,高血压和腹部肥胖的发生率。患有腹部肥胖和高血糖症的人显着显示出较高的低HDL-C水平发生率(双变量分析)。多元线性回归分析发现葡萄糖和甘油三酸酯水平之间呈正相关。收缩压与年龄和腹围显着正相关。腹围与受教育程度呈负相关。结论:该绝经后女性样品中METS的发生率很高,并且与代谢和脂质紊乱有关。由于腹部肥胖与低学历有很大关系,因此迫切需要针对高危人群实施教育计划,以提高对这一问题的认识。

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