The renewed interest in male infertility has led to a more detailed investigation of the seminal vesicles. Seminal vesicle disease were well studied in the first quarter of the 20th century. Symptoms suggestive of seminal vesicle disease are pain with perineal projection and irradiation along the spermatic cord. Secretions can be modified with a blood-stained or purulent appearance. Complementary investigations comprise semen studies and particularly semen culture. Transrectal ultrasound remains the first-line imaging examination. The various seminal vesicle diseases are infection, benign or malignant tumours, malformations, and stones.
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