Synthesis and antimicrobial activities of various N-phenyl-2-{5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazol-2-ylsulfanyl}acetamides

摘要

A new series of various N-phenyl-245-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazol-2-ylsulfanyl}acetamidehave been synthesized by the condensation of 5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazole-2-thiol and 2-chloro-N-(aryl)-acetamides. The novel compound structures have been established on the basis of their substituted N-chloro aryl acetamide derivatives. All the compounds have been characterized by FT-IR, mass spectra, H-1 and C-13 NMR spectroscopy. These new compounds have been evaluated for their in vitro antibacterial and anti-fungal activities.