Although lesbian women have a variety of ways to become mothers, an increasing number of lesbian couples attend fertility centres asking for donor insemination. The practice of inseminating lesbian couples remains a controversial topic within the reproductive medicine world. A review of the literature did not reveal any harmful effects of lesbian motherhood on child development. Furthermore, this treatment is highly effective with an expected cumulative pregnancy rate of 60 after three intra-uterine inseminations with superovulation using clomifene citrate. The only objection to medically assisted procreation in these couples is therefore purely ethical. The extensive experience of the AZ-VUB Centre for Reproductive Medicine that played a pioneer role in this field, is illustrated in this article.
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