Synthesis and biological activity of 1,5-dihydropyridazino3,4-bquinoxalines and a new class of quinolones

摘要

A new class of quinolones, 1,4-dihydro-4-ortopyridazino3,4-bquinoxaline-3 -carboxylic acids and related compounds, were synthesized via oxidation of 1,5-dihydropyridazino3,4-bquinoxalines obtained from 2-hydrazinoquinoxaline 4-oxides. Some of the 1,5-dihydropyridazino3,4-bquinoxalines 1,4-dihydro-4-oxopyridazino 3,4-bquinoxaline-3-carboxylic acids, and related compounds showed biological activity. References: 25