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Novel insights on spontaneous coronary artery dissection

机译:自发性冠状动脉夹层的新颖见解

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Spontaneous coronary artery dissection (SCAD) remains an elusive and challenging clinical entity of unknown etiology eight decades after its initial pathological recognition [1]. Coronary angiography has been classically used for the diagnosis of these patients [2-6]. A radiolucent intimal flap, separating the true lumen from the false lumen, has been considered as the hallmark of the disease [2-6]. Multiple case reports and small retrospective series with limited clinical follow-up have been published but the total number of patients with SCAD reported to date is less than 700 [2-6]. This largely explains the limited information currently available on prevalence, predisposing conditions, pathophysiol-ogy, diagnosis, management and prognosis of patients with SCAD [2-6].
机译:自从最初的病理学认识八年后,自发性冠状动脉夹层术(SCAD)仍然是病因不明的难以捉摸和具有挑战性的临床实体[1]。冠状动脉造影已被经典用于诊断这些患者[2-6]。可以将真腔与假腔分开的不透射线的内膜瓣被认为是该疾病的标志[2-6]。已经发表了多起病例报告和少量的回顾性研究,临床随访有限,但迄今报道的SCAD患者总数不到700例[2-6]。这很大程度上解释了目前有关SCAD患者的患病率,易感性,病理生理,诊断,管理和预后的有限信息[2-6]。

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