机译:ATR 激酶抑制剂 AZD6738 增强放疗后 CD8(+) T 细胞依赖性抗肿瘤活性
Univ Pittsburgh, Sch Pharm, Dept Pharmaceut Sci, Pittsburgh, PA 15261 USA;
Univ Pittsburgh, Sch Med, Dept Microbiol & Mol Genet, Pittsburgh, PA USA;
Inova Ctr Personalized Hlth, Inova Schar Canc Inst, Falls Church, VA USAAstraZeneca, Oncol IMED, DNA Damage Response Biol Area, Cambridge, EnglandUniv Pittsburgh, Sch Med, Dept Immunol, Pittsburgh, PA USAJohns Hopkins Univ, Program Cellular & Mol Med, Dept Radiat Oncol & Mol Radiat Sci, Baltimore, MDUniv Pittsburgh, Sch Med, Dept Radiat Oncol, Pittsburgh, PA USA;
机译:PI3K delta/gamma inhibitor BR101801 extrinsically potentiates effector CD8(+) T cell-dependent antitumor immunity and abscopal effect after local irradiation
机译:Weel kinase inhibitor AZD1775 potentiates CD8+T cell-dependent antitumour activity via dendritic cell activation following a single high dose of irradiation
机译:Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects.
机译:ATR激酶抑制剂AZD6738增强放射后CD8 + T细胞依赖性抗肿瘤活性