Synthesis of novel 2-methyl and 2-cyanomethyl-12-aryl-8,12-dihydro-9H-chromeno3,2-e1,2,4triazolo1,5-cpyrimidin-11(10H)-one derivatives

摘要

2-Methyl and 2-cyanomethyl-12-aryl-8,12-dihydro-9H-chromeno3,2-e1,2,4triazolo1,5-cpyrimidin-11(10H)-one derivatives were synthesised by the cyclisations of acetic anhydride or ethyl cyanoacetate with chromeno2,3-dpyrimidine derivatives, which were obtained by the reactions of hydrazine monohydrate and formimidate derivatives. In addition, 2,9,9-trimethyl12-( p-tolyl)-8,12-dihydro-9H-chromeno3,2-e1,2,4triazolo1,5-cpyrimidin-11(10H)-one and 2-cyanomethyl-12-phenyl-8,12- dihydro-9H-chromeno3,2-e1,2,4triazolo1,5-cpyrimidin-11(10H)-one were further determined by single-crystal X-ray diffraction analysis.