The new Nexera Mikros from Shimadzu is a micro flowrate-compatible liquid chromatograph mass spectrometer. It maintains the durability and operability of LC-MS systems while providing a significant increase in sensitivity. The Nexera Mikros can accommodate a wide range of flowrates, from semi-micro flowrates (100 to 500 uL/min) which are often used for analysis in existing systems, to micro flowrates (1 to 10 uL/min). With this product, Shimadzu is contributing to improving productivity at pharmaceutical companies and clinical contract research organisations. Nexera Mikros achieves at least ten times the sensitivity for target compounds compared to standard LC-MS analysis. This is due to the LC-Mikros, a solvent delivery pump with a new control system to reduce pulsation and deliver a stable solvent flow even at low micro flowrates. In addition, positioning of the ionisation interface has been optimised for more efficient sample introduction into the mass spectrometer.
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