Direct X‐ray determination of the electron‐density profile of the nerve myelin membrane, with paracrystalline lattice distortions taken into account

摘要

Paracrystalline lattice distortions in the nerve myelin membrane system lead to the distortion of theQfunction of the membrane stack and theQ0function of the unit cell. TheQfunction can be expressed as a convolution polynomial of the electron density distribution and the distance‐statistics functions between neighbouring membranes. Fitting this modelQfunction to the experimentalQfunction in a non‐linear least‐squares refinement procedure, one obtains the electron‐density profile of the myelin stack and the distance‐statistics functions. Elimination of the distance statistics permits the calculation of the undistortedQ0function, the deconvolution of which makes possible a unique determination of the electron density distribution of the