ABSTRACTThe relationship of dietary vitamin C to that in the urine has not been established. Vitamin C intake and 24‐hr urinary 1‐ascorbate excretion were measured in healthy, human, Caucasian, female subjects (ages 22–26 yr). Modifications were made in the measurement of 1‐ascorbic acid in the urine. The correlation of dietary vitamin C to that excreted in the urine was highly significant (P<0.001; r = 0.952). The regression equation is: y = ‐1.2970 + 0.1863x. The average intake of vitamin C was 146.5 ± 117.6 mg (standard deviation) (range 42–424 and the average amount in a 24‐hr urine sample was 26.0 ± 23.0 mg (range 5–71). The average percentage of dietary intake excreted per day was 17.04 ± 9.43 (range 6.1–29.4). Data presented here should help establish guidelines for interpreting urinary 1‐ascorbic acid concentrations. If dietary data are available, it is suggested that these guidelines be expressed as a percentage of intake. Addi
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