A 50-year-old man diagnosed with early-stage prostate cancer underwent a radical prostatectomy in 1992. His prostate-specific antigen (PSA) decreased to an undetectable level after operation, but 5 years later it had increased to 0.3 ng/ml. Results of a physical examination and bone scan were unremarkable. The time course of the postoperative PSA increase was suggestive of local recurrence. A ProstaScint scan from March 1997 showed abnormal activity only in the prostatic fossa, consistent with local recurrence. He underwent salvage radiation therapy to the prostate bed, which ended in June 1997. His serum PSA returned to undetectable levels and he has since remained clinically disease free. A repeated ProstaScint scan from July 1998 revealed no evidence of disease.
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