Hot-To-Cold Transition of Intrasplenic Lymphoma After Chemotherapy

摘要

A 52-year-old man with non-Hodgkinrsquo;s lymphoma (large-cell type) was treated with chemotherapy and his disease went into remission. When seen 6 years later because of abdominal discomfort, a chest radiograph revealed a left pleural effusion. CT scans showed mediastinal plus paratracheal adenopathy and an 8-cm splenic mass. A radiogallium study revealed that the splenic mass was Ga-67 avid. Chemotherapy was instituted. Eight weeks after the first study, repeated radiogallium imaging showed a cold defect in the area of the previous avid splenic uptake.