Facile and regioselective synthesis of thiazolidin-4-one derivatives catalyzed by basic ionic liquid bmimOH under ultrasonic irradiation

摘要

2-Iminothiazolidin-4-one derivatives were synthesized regioselectively in good to high yields by condensation of N,N'-disubstituted thioureas and ethyl chloroacetate in the presence of basic ionic liquid bmimOH as a catalyst under conventional and ultrasonic irradiation conditions. Under ultrasonic irradiation, the reaction furnished the desired 2-iminothiazolidinones in higher yields (76-87) and lower reaction times (30-55 min).