Phosphate-Mediated Enyne Synthesis from Allenols

摘要

abstract_textpAn efficient synthetic pathway to enyne derivatives from readily-available allenols has been accomplished using trimethyl phosphate as an inexpensive and stable activator of the hydroxy groups of the allenols in the presence of sodium hydride. The present method could be applied to various allenol derivatives to produce a variety of functionalized-enyne products./p/abstract_text