Unprecedented stereoselectivity in a reaction of a novel diboron compound — 1,6-bis(dialkylboryl)-2,4-hexadiene with carbonyl compounds

摘要

Arylboration of carbonyl compounds with a novel diboron reagent — 1,6-bis(dipropylboryl)-2,4-hexadiene — proceeds in a regio- and stereospecific way to give exclusivelyd,l-diastereomers of the corresponding 2,3-divinylsubstituted 1,4-diols. Their iodocyclization allowed preparation of 3,7-dioxabicyclo3.3.0octane derivatives withcis-junction of the tetrahydrofuran ri