Gelatin Solubility and Processing in Ionic Liquids: An Approach Towards Waste to Utilization

摘要

abstract_textpWe have investigated the solubility behavior of protein gelatin, in neat protic ionic liquids (ILs) alkyl ammonium nitrates, (C-n NH3NO3, n=2, 3, 4) and their reciprocal binary mixtures with C(4)mimCl(1-butyl-3-methyl imidazolium chloride). Very high dissolution of gelatin could be achieved in C2NH3 NO3(Ethylammonium nitrate). High solvating ability of C2NH3 NO3 towards gelatin was utilized to process solid pharmaceutical waste of gelatin capsules by dissolving in C2NH3NO3 for the recovery of pure gelatin. The recovered gelatin was further processed to prepare gelatin/Ag2O nano-composite in a mixed IL system, C2NH3NO3 + C(4)mimCl. The prepared nanocomposite exhibited excellent antimicrobial activity on gram negative bacteria pseudomonas aeruginosa MTCC NO-1688 and Escherichia coli MTCC NO-42 and therefore, can be useful for potential biomedical applications. The developed process is a worthy alternative strategy for "waste to utilization" of gelatin pharmaceutical scrap./p/abstract_text