Can Evolutionary Tools Reliably Tell Us about Dengue Virus' Past Outbreaks?

摘要

The mosquito-borne dengue virus is most prevalent in southeastern Asia, with four common strains or “serotypes” of the virus infecting up to 10 of children in Vietnam annually. Dengue virus is a major challenge for evolutionary biologists because of its complex ecology and rapidly changing disease dynamics. But can evolutionary models become a reliable tool for epidemiologists studying infectious disease?.