机译:通过对接研究、分子动力学模拟和体内筛选发现锥虫生物活性先导物
Univ Nigeria, Fac Pharmaceut Sci, Dept Pharmaceut & Med Chem, Nsukka, Nigeria;
Univ Nigeria, Dept Pharmacol & Toxicol, Nsukka, Nigeria;
antitrypanosoma; docking; molecular dynamics; invivo; screening; TRYPANOTHIONE REDUCTASE; ANTITRYPANOSOMAL ACTIVITY; ANTIPROTOZOAL ACTIVITIES; AFRICAN TRYPANOSOMES; INHIBITION POTENCY; BINDING MODE; AGENTS; PLANTS;