Dichlorination of Alkenes Using 1,3-Dichloro-5,5-Dimethylhydantoin and ZnCl2

摘要

Electron-deficient and electron-rich alkenes can be efficiently converted to vicinal dichlorides employing a mixture of 1,3-dichloro-5,5-dimethylhydantoin (DCDMH) and zinc chloride. This straightforward protocol offers an easier to handle and safer alternative to the use of chlorine gas or other common chlorinating agents. Experimental evidences suggest that the solubility of the chloride salt is essential for the formation of a chlorine/trichloride anion as the effective chlorinating agent.