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Xerostomia in older adults: a longitudinal study

机译:老年人口干症:一项纵向研究

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Although xerostomia in older adults has received substantial research attention, there have been few longitudinal studies of non‐patient populations. Consequently, little is known about the incidence or course of this condition among this group. This paper reports the results of a longitudinal study designed to address these issues. In 1989, data on xerostomia were collected from 907 randomly‐selected community dwelling adults aged 50 years and over. Three years later, 611 (71 of those presumed to be alive) were followed‐up and data on xerostomia collected again. At baseline, 15.5 of these 611 subjects reported xerostomia, while at follow‐up this had risen to 29.5. The majority of the latter (115/180) were incident cases, reporting xerostomia only at follow‐up, while the remainder were chronic cases, reporting xerostomia at both baseline and follow‐up. A crude estimate of the three‐year incidence rate was 22.5. In a logistic regression analysis, three baseline variables were associated with incidence; older subjects, those with one or more chronic medical conditions and those reporting their general health as poor were more likely to develop xerostomia. In a similar analysis, age was the only variable associated with chronicity, with older subjects more likely to be chronic cases. The data also suggest that the onset of xerostomia was associated with an increase in other oral symptoms and problems with eating, communication and socia
机译:尽管老年人口干症已受到大量研究关注,但针对非患者人群的纵向研究很少。因此,对该组中这种疾病的发病率或病程知之甚少。本文报告了旨在解决这些问题的纵向研究的结果。1989 年,从随机选择的 907 名 50 岁及以上的社区居住成年人中收集了口干症数据。三年后,对611人(71%的推测还活着的人)进行了随访,并再次收集了口干症的数据。在基线时,这 611 名受试者中有 15.5% 报告了口干症,而在随访时,这一比例上升到 29.5%。后者大多数(115/180)是事件病例,仅在随访时报告口干症,而其余为慢性病例,在基线和随访时均报告口干症。三年发病率的粗略估计为 22.5%。在逻辑回归分析中,三个基线变量与发病率相关;老年受试者、患有一种或多种慢性疾病的人以及报告其总体健康状况较差的人更有可能患上口干症。在类似的分析中,年龄是与慢性病相关的唯一变量,年龄较大的受试者更有可能是慢性病患者。数据还表明,口干症的发作与其他口腔症状以及饮食、沟通和社交问题的增加有关

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