HOTf-Catalyzed, Solvent-Free Oxyarylation of Ynol Ethers and Thioethers

摘要

A novel HOTf-catalyzed oxyarylation of ynol ethers and thioethers has been realized with aryl sulfoxides as the oxyarylating reagents, providing a-arylated esters or thioesters in good to excellent yields. Notably, all atoms of the starting materials were incorporated in the product (100 atom economy) and the reaction proceeded under very mild conditions. It was found that the reaction can be ran "under air and that the best yields are obtained under solvent-free conditions.