Diabetic patients have a 15 lifetime risk of developing a foot ulcer and have a 15 risk of developing a lower extremity amputation. Amputation is preceded by non-healing foot wounds in 85 of cases 1. The ulcerated diabetic foot may be considered the complication of the peripheral neuropathy (PN) and/or peripheral arterial disease (PAD). Several studies showed that diabetic patients with PN are at risk of foot ulceration and indeed true neuropathic ulceration is found in almost 50 of the patients with a new foot ulcer according to eurodiale 2. Those with PAD are at risk of foot amputation and ischemic lesions are found in the other 50 of patients with foot ulceration. However true ischemic ulcers are observed only in 15 of cases. The remaining 35 have both PAD and PN present at the same time: neuroischemic ulcers 2.
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