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Checkpoints and restriction points in bacteria and eukaryotic cells

机译:细菌和真核细胞中的检查点和限制点

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摘要

Bacterial checkpoints, analogous to those proposed to exist in eukaryotic cells, offer insights into.the definition of a checkpoint. Examination of bacterial "checkpoint" or arrest phenomena illustrate problems with a too-casual application of the checkpoint idea to eukaryotic phenomena. The question raised here is whether there are cellular processes that "check" whether a cellular process is completed. It is possible that many eukaryotic "checkpoints" may not have "checking" functions. Some of the ubiquitous checkpoint phenomena widely described may be merely the result of the inherent incompleteness of earlier events preventing the initiation of subsequent events.
机译:细菌检查点,类似于那些被提议存在于真核细胞中的细菌检查点,提供了对检查点定义的见解。对细菌“检查点”或停滞现象的检查表明,将检查点思想过于随意地应用于真核现象的问题。这里提出的问题是,是否存在“检查”细胞过程是否完成的细胞过程。许多真核生物的“检查点”可能没有“检查”功能。一些被广泛描述的无处不在的检查点现象可能仅仅是早期事件固有的不完整性阻止后续事件启动的结果。

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