Isolation of a Caffeine‐Resistant Mutant ofAspergillus parasiticus

摘要

ABSTRACTA caffeine‐resistant mutant ofAspergillus parasiticusNRRL 2999 was isolated and subsequently designated strain BCR1. The mutant strain grew in the presence of>8 mg/mL caffeine, while growth of the parent strain was delayed by 1 mg/mL and inhibited by 2 mg/mL. Strain BCR1 produced abundant amounts of aflatoxin only when cultured in media containing caffeine. Residual caffeine analyses indicated that caffeine‐resistance in BCR1 was not due to the metabolic elimination of caffe