Abstract.The relation between donor alanine aminotransferase (ALT) and recipient post‐transfusion hepatitis (PTH) non‐A, non‐B was studied in patients tested before and 6 and 12 weeks after transfusion. The minimum ALT criterion for PTH was 105 IU/1 (>2.5 times the upper normal of 42 IU/1). In 8.8 of donors, ALT was>42 IU/1, and in 2.3 ALT was>63 IU/1, i.e., 1.5 times elevated. PTH non‐A, non‐B occurred in 14 of 742 recipients. The PTH incidence increased when donor ALT was above 63 IU/1 (1.5 vs. 5.6; p<0.05). However, if the confounding factor of volume variations was compensated for, elevated donor ALT and PTH were only statistically linked among recipients<70 years (p<0.02; Mantel‐Hae
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