Miniaturized liquid separation techniques in bioanalysis

摘要

The trend towards miniaturization in analytical chemistry leads one to realize that smaller is better. This holds true in the field of bioanalysis. The list of biologically relevant analytes is diverse: (1) biopolymers: DNA, RNA, protein, carbohydrate, (2) biomonomers: amino acids, nucleic acids, monosaccharides, lipids, and (3) other molecules. The drive for core information in kinetics, thermodynamics, and composition provides the ability to answer diverse questions related to mechanism, function, purpose, design, disruption, or interruption of biological processes.