AbstractThis study reveals that in rheumatoid joint disease the total osmotic pressure of synovial fluid tends to be lower than, or equal to, that of plasma. With local articular or general systemic improvement the total osmotic pressures of synovial fluid and plasma tend to increase, and that of synovial fluid may exceed that of plasma. The colloid osmotic pressure of synovial fluid from joints of patients with rheumatoid arthritis was lower than that of plasma.
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