Abstract.An automated assay of anti‐P1allohemagglutinins has been carried out on 133 P2subjects: 13 with acute hepatic distomiasis (Fascioliasis), 20 with hydatidosis and 100 healthy blood donors. Anti‐P1were detected in 100 of the distomatid sera, in 50 of the hydatid and in 29 of the healthy individuals. When compared to a reference serum test (anti‐P1standard), their concentration was found to be weak in healthy subjects, moderate in hydatidosis and exceptionally increased in acute distomiasis (up to 5–6 times the standard anti‐P1level). The 2‐mercaptoethanol treatment showed that even the increased distomatid anti‐P1sera were of an IgM nature. The respective origin, synthesis and strength of these allohemagglutinins are discussed and the advantages of using distomatid IgM anti‐P1as human sera test
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