Solubility enhancement of triflumizole by host-guest interaction with β-cyclodextrin

摘要

The solubility enhancement of triflumizole, a systemic fungicide, by β-cyclodextrin inclusion complexation was investigated by electron absorption spectroscopy. The respective association constant determined by different methods was estimated to 470±20M−1in aqueous solution. A model for the host-guest complexation was deduced by molecular calculati