Potential Therapeutic Applications of MDA-9/Syntenin-NF-kappa B-RKIP Loop in Human Liver Carcinoma

摘要

Background: Overexpression of MDA-9/Syntenin occurs in multiple human cancer cell lines and is associated with higher grade of tumor classification, invasiveness and metastasis. In some cases, its role in cancer biology depends on relationships between MDA-9/Syntenin and NF-kappa B.