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The Effect of the Impeller‐Driver Magnetic Coupling Distance on Hemolysis in a Compact Centrifugal Pump

机译:叶轮-驱动磁耦合距离对紧凑型离心泵溶血的影响

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Abstract:Blood trauma is one of the important performance parameters of centrifugal pumps. To investigate the blood trauma induced by these pumps, in vitro hemolysis tests have become an important procedure and are increasingly used for pump development and comparisons. The Baylor compact eccentric inlet port (C1E) centrifugal blood pump was developed as a long‐term centrifugal ventricular assist device (VAD) as well as a cardiopulmonary bypass pump (CPB). The Baylor C1E pump incorporates a seal‐less design with a blood stagnation‐free structure. This pump can provide flows of 5 L/min against 350 mm Hg of total pressure head at 2,600 revolutions per minute. The pump impeller is magnetically coupled to the driver magnet in a seal‐less manner. The latest hemolysis study revealed that hemolysis may be affected by the gap distance between the driver and the impeller magnet. The purpose of this study was to verify the effect of the magnetic coupling distance on the normalized index of hemolysis (NIH) with the C1E model and to obtain an optimal gap distance. The NIH value was clearly decreased by alteration of the magnetic coupling distance from 7.7 to 9.7 mm in CPB and left ventricular assist device (LVAD) conditions. The NIH, when using the pump as an LVAD condition, was reduced to a level of 0.0056 from 0.095 when the magnetic coupling distance was extended. The same results were also obtained when the pumps were used in a CPB condition. The magnetic coupling distance is an important factor for the C1E model in terms of hemolysis. Different coupling forces effect the bearings and impeller stability. These results suggest that an optimal driving condition with a proper magnetic coupling and an optimal force between the impeller and driver is necessary to develop an atraumatic centrifug
机译:摘要:血外伤是离心泵的重要性能参数之一。为了研究这些泵引起的血液创伤,体外溶血试验已成为一项重要的程序,并越来越多地用于泵的开发和比较。贝勒紧凑型偏心进气口 (C1E) 离心血泵被开发为长期离心心室辅助装置 (VAD) 和体外循环泵 (CPB)。贝勒 C1E 泵采用无密封设计和无血滞结构。该泵可以以每分钟 2,600 转的速度提供 5 L/min 的总压头和 350 mm Hg 的总压头的流量。泵叶轮以无密封方式磁耦合到驱动磁铁上。最新的溶血研究表明,溶血可能受到驱动器和叶轮磁铁之间的间隙距离的影响。本研究的目的是验证磁耦合距离对C1E模型的归一化溶血指数(NIH)的影响,并获得最佳间隙距离。在 CPB 和左心室辅助装置 (LVAD) 条件下,通过将磁耦合距离从 7.7 mm 改变到 9.7 mm,NIH 值明显降低。当使用泵作为LVAD条件时,当磁耦合距离延长时,NIH从0.095降低到0.0056的水平。当泵在CPB条件下使用时,也获得了相同的结果。就溶血而言,磁耦合距离是C1E模型的重要因素。不同的耦合力会影响轴承和叶轮的稳定性。这些结果表明,开发非创伤离心机需要具有适当磁耦合的最佳磁耦合和叶轮和驱动器之间的最佳力的最佳驱动条件

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