Chemiluminescent labels have been shown to be interesting alternatives to radioisotope labels. Disadvantages of the latter are preparation of e.g. labelled protein/peptides every four to six weeks, and problems with storage and disposal. Amino-Butyl-Ethyl-Isoluminol(ABEI) was attached to the alpha-amino function of the N-terminal amino acid residue of oxytocin; this complex was used in immunoassays for oxytocin. This non-isotopic label did not require heating at 60#xB0;C for optimal light-signal development, a procedure usually required for chemiluminescent labels.
展开▼
