Sensitivity of methicillin‐resistantStaphylococcus aureusstrains to some antibiotics, antiseptics and disinfectants

摘要

The effects of antibiotics, antiseptics and disinfectants against some methicillin resistant (MRSA) and methicillin‐sensitive (MSSA)Staphylococcus aureusstrains have been studied. The MRSA and MSSA strains were equally sensitive to phenols, esters of para(4)‐hydroxybenzoit acid and chlorhexidine but MRSA strains were slightly more resistant to quaternary ammonium compounds and considerably more so to dibromopropamidine isothionate. Some MRSA strains were also resistant to phenylmercuric nitrate (but not another organomercurial, thiomersal), mercuric chloride and cadmium chloride. All MRSA strains produced β‐lactamase. Strains from the Royal Free Hospital, London were highly resistant to β‐lactam antibiotics, erythromycin, trimethoprim and tetracyctines but were sensitive to other antibiotics. One strain from the University Hospital of Wales, Cardiff was resistant to gentamicin but sensitive to tetracycline and tri