LincRNAs: Systemic Computational Identification and Functional Exploration

摘要

Background: The mammalian genome is pervasively transcribed and produces a large number of non-coding products compared to protein-coding genes. One novel sub-class of non-coding RNAs, long intergenic non-coding RNAs (lincRNAs), has been identified in mammalian genomes and is thought to play multiple roles in gene regulation and other cellular processes, and even human disease.