A 57-year-old woman was referred to our Endocrine Unit 3 years after she underwent total thyroidectomy for a large non-toxic multinodular goiter with tracheal deviation. At that time histology was negative for malignancy. She had no family history of thyroid disease. At the time of our observation no palpable neck mass was present, but neck ultrasound imaging study revealed a left lateral solid cervical mass (8 x 13 x 14 mm), with features of a lymph node, strongly hypoechoic, lacking in homogeneity, containing several microcalcifications and lack of visibility of the hilum (Fig. 1). The patient gave informed consent to the study and US-FNAB of this mass with thyroglobulin assay in the wash-out liquid were performed. Thyroglobulin (Tg) value of >3 0.000 ng/ml in the wash-out liquid of the needle and the presence of epithelial follicular cells in the specimen suggested the presence of proliferating thyroid cells 1, 2.
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