Antimicrobial properties of delmopinol against oral bacteria

摘要

Antimicrobial properties of the morpholine derivative delmopinol hydrochloride were investigatedin vitro. Minimum inhibitory concentrations were measured for a range of oral bacteria by broth and agar dilution techniques and minimum bactericidal concentrations were measured in broth. The rate of kill was investigated by determination and analysis of kill curves. The results indicated that delmopinol is a relatively weak antimicrobial in comparison with chlorhexidine. However, it may selectively affect certain species of oral bacteria which are of importance in plaque formation.