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Metabolic Syndrome and Asthma

机译:代谢综合征和哮喘

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摘要

Metabolic syndrome (MetS) is a syndrome that involves at least three disorders dyslipidemia, insulin resistance, obesity and/or hypertension. MetS has been associated with several chronic diseases in the adulthood; however, in the recent years, the syndrome was redefined in children. Girls with early menarche and asthma, and children with MetS and asthma that reach adulthood appear to have higher risk to develop severe or difficult to control asthma and a higher probability to suffer cardiovascular diseases. It has been proposed that patients with MetS and endocrinological disorders should be considered a different entity in which pharmacologic treatment should be adjusted according to the individual. Recent patents on the field have addressed new issues on how endocrine control should be managed along with asthma therapeutics. In the near future, new approaches should decrease the high morbidity and mortality associated to these types of patients.
机译:代谢综合征 (MetS) 是一种涉及至少三种疾病的综合征:血脂异常、胰岛素抵抗、肥胖和/或高血压。MetS 与成年期的几种慢性疾病有关;然而,近年来,该综合征在儿童中被重新定义。月经初潮早起的女孩,以及成年后患有MetS和哮喘的儿童,患上严重或难以控制的哮喘的风险更高,患心血管疾病的可能性更高。有人提出,MetS 和内分泌疾病患者应被视为不同的实体,应根据个体调整药物治疗。该领域最近的专利解决了如何与哮喘治疗一起管理内分泌控制的新问题。在不久的将来,新方法应能降低与这些类型患者相关的高发病率和死亡率。

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