The genetic basis of resistance and sensitivity to the meiotic drive geneDin the mosquitoAedes aegyptiL.

摘要

A study has been made on the genetic basis of meiotic drive at the Distorter (D) locus which, in coupling with the male-determining gene (or region)Mon the Y chromosome, causes production of excess male progeny. Its effect is regulated by the sensitivity/resistance of the X chromosome. This study demonstrates that there are two major loci controlling resistance/sensitivity to MD: (1) themgene (or region) on the X chromosome (allelic withM) which may be eithermRormS(resistant or sensitive), (2) thet(tolerance) gene (or genes) which recombines withmand, if present, largely counteracts the effect ofmS. There is also evidence that MD itself is capable of limited adaptation.